2007. Antonio Cassone (I). "Antifungal vaccines"

In 2007, during the 3rd TIMM in Torino, Italy, the E. Drouhet memorial lecture by Prof. Antonio Cassone (Italy) was given with the title "Antifungal vaccines".

From Mycology Newsletter 2007, P. 9
At the 3rd Trends in Medical Mycology the prestigious E. Drohuet Lecture, an international recognition for the most distinguished researchers in the field, was given by Antonio Cassone, from the Istituto Superiore di Sanità, Rome, Italy, who intrigued the audience of the Plenary Session 1 with the talk “Antifungal vaccines”.

After a comprehensive review of the frustrating challenge that the identification of suitable fungal targets may represent for vaccinologists, Prof. Cassone has proposed a revolutionary approach for protecting immunocompromised patients even against multiple mycoses (i.e., candidiasis, aspergillosis, cryptococcosis) with a single, well-defined beta-glucan-protein conjugate vaccine eliciting antibodies exerting direct antifungal effects in vitro and conferring passive transfer of immunity to naive animals that was prevented by adsorption of antibodies on beta-glucan particles